Hi,<br><br>I am modelling a tetrameric protein (ion channel). I want to evaluate the models, but  I have read that the DOPE assesment is not good for multi chain proteins (<a href="http://www.salilab.org/modeller/9v6/manual/node242.html">http://www.salilab.org/modeller/9v6/manual/node242.html</a>). Then, how is the best way to evaluate them? Each chain should be evaluated independently? Should I take only the best molpdf score?<br>
<br>In the case of taking only the best molpdf, are there no way for an optimization with DOPE like the Tutorial says? <br><br>Thanks,<br><br>Omar<br>