Dear MODELLER experts,<br>  <br>  I have a target protein, whose X-ray structure is PARTIALLY available (the middle part, named domain B).&nbsp;&nbsp; There are two big regions missing (domain A &amp; C) in the crystal structure, with more than 50 residues in each&nbsp; I would like to use MODELLER to model domain A &amp; C,&nbsp; and there are templates available.&nbsp; I wonder if it is possible to include THE CONTENT OF domain B.&nbsp; in another word, to create a complete model of A-B-C while keep the coordinates of B domain fixed.<br>  <br>  Any help/information will be greatly appreciated.<br>  <br>  Shirley<br>   <div>     </div> <hr size="1"><p>__________________________________________________<br>Do You Yahoo!?<br>Tired of spam?  Yahoo! Mail has the best spam protection around <br>http://mail.yahoo.com