14 Aug
2002
14 Aug
'02
4:38 p.m.
>From Eric:
Hi Pedro; You can tell modeller to make particular disulfide bridges using this sub routine:
SUBROUTINE ROUTINE = 'special_patches' PATCH RESIDUE_TYPE = 'DISU', RESIDUE_IDS = '160: ' '190: ' # 160 is the cystein number on the sequence PATCH RESIDUE_TYPE = 'DISU', RESIDUE_IDS = '122: ' '206: ' PATCH RESIDUE_TYPE = 'DISU', RESIDUE_IDS = '76: ' '128: ' RETURN END_SUBROUTINE
Good luck Eric
------------------------------------ Dr Eric Feyfant Computational Chemist Departement of Biological Chemistry Wyeth Research 85 Bolton St. Cambridge, MA 02140 tel: +1 617 665 8987 fax: +1 617 665 8993 email: efeyfant@wyeth.com