Now i have to model a protein with 500 amino acid residues, for which there
are no pdb matches in the pdb database. So i have gone for pfam domain search. I
found that a domain with 500 residues and from 30-494 is aligning
with my sequence with a e value of 3e-11. Can i take this portion as
a template for modelling? and what should i do for the remaining amino
acids (1.e) 1-29 and 494-500.?
should i follow the steps involved in advance modelling?
please do explain me the steps involved
with regards
sankari