Thank you, my loop refinement calculation has ended successfully now, however...<br><br><div class="gmail_quote"><blockquote class="gmail_quote" style="border-left: 1px solid rgb(204, 204, 204); margin: 0pt 0pt 0pt 0.8ex; padding-left: 1ex;">


You&#39;re only building one loop model. I&#39;d recommend building several, so<br>
that you can sample the conformational space more effectively. This also<br>
allows for the possibility that some of the models are not produced due<br>
to optimizer failure, as you have discovered.<br>
<br>
</blockquote></div><br>OK, so after I get a bunch of models with a refined loop, how can I tell which one is better<br>than the others? <br clear="all"><br><br><br>-- <br> &nbsp; &nbsp; &nbsp; &nbsp; 0 &nbsp; &nbsp; | &nbsp;Mauricio Carrillo Tripp, PhD<br>

 &nbsp; &nbsp; &nbsp;/ &nbsp; &nbsp; &nbsp; &nbsp; | &nbsp; &nbsp; Department of Molecular Biology, TPC6<br> &nbsp;0 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;| &nbsp; &nbsp; The Scripps Research Institute<br> &nbsp; &nbsp; &nbsp;\ &nbsp; &nbsp; &nbsp; &nbsp; | &nbsp; &nbsp; 10550 North Torrey Pines Road<br> &nbsp; &nbsp; &nbsp; &nbsp; 0 &nbsp; &nbsp; | &nbsp; &nbsp; La Jolla, California 92037<br>



 &nbsp; &nbsp; &nbsp;/ &nbsp; &nbsp; &nbsp; &nbsp; |<br> &nbsp;0 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;|<br><br>