7 Mar
2002
7 Mar
'02
2:13 a.m.
Hi Modeller Users and Support
if this is a resend, please forgive me - I tried to send this yesterday but it looked like it bounced. The question is: Is there any efficient, systematic way to "soften" or "loosen" homology derived restraints? What I have in mind is to model some (SCR) segments with regular homology derived restraints and others (SVR) with, say Calpha or backbone from the template only, less stringent geometric homology derived restraints and more thorough refinement (i.e. the halfway point between regular homology modelling and loop modelling). Short of editing the restraints by hand - any efficinet way of doing so? thanksalot, margot