Hi I got it Thanks Ben.

Regards,
Vinayak

From: Modeller Caretaker
Sent: ‎17/‎11/‎2015 01:14
To: Kalantzi Alexandra Styliani; modeller_usage@salilab.org
Subject: Re: [modeller_usage] Fixed amino acids?

On 11/16/15 6:40 AM, Kalantzi Alexandra Styliani wrote:
> I would like to build a protein structure based on multiple
> homologous proteins. But is it possible to keep few amino acids (main
> and side chain) of a homologous structure fixed and build the rest of
> the structure around these?

Sure, you can ask Modeller to only refine part of the model; see
http://salilab.org/modeller/9.15/manual/node23.html

Ben Webb, Modeller Caretaker
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modeller-care@salilab.org             https://salilab.org/modeller/
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