Is the DOPE score good for evaluating transmembrane proteins model-structures?
7 Dec
2012
7 Dec
'12
7:08 a.m.
Hi,
I was wondering whether I can use the DOPE score to evaluate models of transmembrane proteins?
Thank you, Doran
10 Dec
10 Dec
6:07 p.m.
On 12/7/12 7:08 AM, doranhen@post.tau.ac.il wrote: > I was wondering whether I can use the DOPE score to evaluate models of > transmembrane proteins?
The DOPE score is a statistical potential. As such it tells you how similar your model is to structures in its training set. DOPE's training set included only single chain globular proteins. So it *might* work for transmembrane proteins (or globular proteins with multiple chains) but we can't state that it does with any conviction.
Ben Webb, Modeller Caretaker
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