Dear Modellers, For E-value and alignment scoring systems, we use the parameters lambda and K. Specifying these scores is must for a scoring system. So what is/are the normal set of these parameters used in PSI-BLAST/CS-BLAST/HHPRED or other profile inclusion based template searching methods? Tell me the commonly used values for these two parameters lambda and K for the calculation of alignment scores.

Thanks Ashish

Ashish Runthala, Lecturer, Structural Biology Cell, Biological Sciences Group, BITS, Pilani Rajasthan, INDIA