7 Nov
2013
7 Nov
'13
2:06 a.m.
How can i build a homology model using template,my template is a crystal structure of a chimeric protein. though it has a 94% query coverage and 48% identity with my target sequence. sequence alignment of non chimeric protein as a whole is very much identical.Can i use the chimeric crystal structure for modelling?
7 Nov
7 Nov
4:18 p.m.
On 11/7/13 2:06 AM, pr@tibh@ wrote: > How can i build a homology model using template,my template is a crystal > structure of a chimeric protein. though it has a 94% query coverage and > 48% identity with my target sequence. sequence alignment of non chimeric > protein as a whole is very much identical.Can i use the chimeric crystal > structure for modelling?
Yes, that should be fine.
Ben Webb, Modeller Caretaker
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