Hi,

I would like to ask a few questions:

1. I wonder if somebody succeeded with modelling of a protein with "multiple and not overlapping templates" (sorry for asking an old question) with Modeller. I have two situations about this issue: (1) model a two domain protein from two separate pdb files, there is a gap about 10 residues between them; and (2) model a two subunits protein from one pdb file which contains many subunits. I would appreciate very much if I can share your experience (How the top file is and how the alignment file should be?). Which program is the best for these kinds of modeling?

2. Has anybody compiled a linux huge version? I would like to try on the above examples.

3. Does anybody know a modeling program in which you can do ab initio modeling for short peptide (30-60 residues)?

Thank you very much for your kind attention.

Sincerely yours,

Xiao-Ping Zhang

------------------------------------------------ Xiao-Ping Zhang Department of Biochemistry Stockholm University 106 91 Stockholm Sweden

Phone: 46-08-162582 / 162472 Fax: 46-08-153679 e-mail: zhang@biokemi.su.se