Assess model quality with multi chains
Dear all,
I have remodelled a loop on a tetramer model, and kicked out 40 of 100 loops which had bad objective functions. As pointed out in the manual, either DOPE or GA341 function is recommended to assess a model with multi chains. So how to assess the 60 loop models?
Many thnx.
Binbin
bmbbl@leeds.ac.uk wrote: > I have remodelled a loop on a tetramer model, and kicked out 40 of 100 loops > which had bad objective functions. As pointed out in the manual, either DOPE > or GA341 function is recommended to assess a model with multi chains. So how to > assess the 60 loop models?
I guess you mean "is NOT recommended".
You can certainly use either method to assess the models (although DOPE will probably be more discriminating than GA341). It's simply that no multi-chain models were included in the benchmark set for either method, so we don't know how reliable they are. But if they work for you...
Ben Webb, Modeller Caretaker
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