Yes, the modweb models are currently based on a single template only. A future version of ModWeb will return models based on multiple templates. So for now, using MODELLER in a manual fashion will probably result in more accurate models depending on the quality of the alignments and templates.

Eswar.

--- Eswar Narayanan, Ph.D Mission Bay Genentech Hall 600 16th Street, Suite N474Q University of California, San Francisco San Francisco, CA 94143-2240 (CA 94158 for courier) Tel +1 (415) 514-4233; Fax +1 (415) 514-4231 http://www.salilab.org/~eashwar

> -----Original Message----- > From: modeller_usage-bounces@salilab.org [mailto:modeller_usage- > bounces@salilab.org] On Behalf Of alarcon@lncc.br > Sent: Monday, March 15, 2004 12:34 PM > To: modeller_usage@salilab.org > Subject: [modeller_usage] ModWeb question > > Dear All > > When sending a query sequence to modweb, this will suggest a > tridimensional > model homology-related to a specific template (which has a experimental > structure determined). The question is ; > When using Modeller stand alone we can make an alignment between our query > sequence and several templates in order to better define regions of > structural > similarity. ModWeb works also in this way ? I mean, the model contructed > for the > query sequence is based lonely in one template ? So, is correct to assume > that > the ModWeb procedure is less accurate than the modeller when used > "manually" due > the one-template basis of calculation? > Thanks in advance > > Frank Alarcon > > ------------------------------------------------- > This mail sent through IMP: http://horde.org/imp/ > _______________________________________________ > modeller_usage mailing list > modeller_usage@salilab.org > http://salilab.org/mailman/listinfo/modeller_usage