Modelling of Homotrimeric protein without biological assembly
17 Jan
2018
17 Jan
'18
11:10 p.m.
Actually I want to build a homology model of a human homotrimeric protein from a FASTA sequences. After BLAST I got a template which is 91% identical but it is originated from Mouse organism. and it is cryo EM structure.From there, I build a single monomeric chain of that human protein by Homology modelling. But it doesn't contain any biological assembly or asymmetric unit. So that, i am unable to build its trimeric structure. so, can you help me in two sections;1) how to build its homotrimeric structure?2) is there any way to generate the biological assembly coordinates from homology protein?Thanks in advance.Best regards.
2530
Age (days ago)
2530
Last active (days ago)
0 comments
1 participants
participants (1)
-
Sourav Pal