7 Dec
1998
7 Dec
'98
5:16 p.m.
I am trying to model a heterotrimeric protein with Modeller. How do I designate the different chains? My template molecule contains three chains, as does the model I'm trying to make. When I use Modeller I get a single chain which distorts my overall tertiary structure. Do I have to model each chain individually or am I missing something?
Jeff
Jeffrey P. Jones, Associate Professor of Chemistry Room 477 Fulmer Hall, Washington State University Pullman WA 99164-4630, jpj@wsu.edu http://cyp.chem.wsu.edu/~jpj/jones_group.html (509) 335-5983, Fax (509) 335-8867
7 Dec
7 Dec
5:58 p.m.
Hi,
In the alignment the sequences of each monomer must be separated by a chain break character "/" (slash). That should solve the problem.
Best Wishes,
Roberto
--
Roberto Sanchez | phone : (212) 327 7206
The Rockefeller University | fax : (212) 327 7540
1230 York Avenue, Box 38 | e-mail: sancher@rockvax.rockefeller.edu
New York, NY 10021-6399 | http://salilab.org
"Jeffrey P. Jones" wrote:
>
> I am trying to model a heterotrimeric protein with Modeller. How do I
> designate the different chains? My template molecule contains three chains,
> as does the model I'm trying to make. When I use Modeller I get a single
> chain which distorts my overall tertiary structure. Do I have to model each
> chain individually or am I missing something?
>
> Jeff
>
> Jeffrey P. Jones, Associate Professor of Chemistry
> Room 477 Fulmer Hall, Washington State University
> Pullman WA 99164-4630, jpj@wsu.edu
> http://cyp.chem.wsu.edu/~jpj/jones_group.html
> (509) 335-5983, Fax (509) 335-8867
9480
Age (days ago)
9480
Last active (days ago)
1 comments
2 participants
participants (2)
-
Jeffrey P. Jones -
Roberto Sanchez