GPCRs and iterative modeling
19 Apr
2014
19 Apr
'14
6:01 a.m.
Dear modeller users!
Inspired by modeller's iterative tutorial I wounder to know more about MOULDING concept of modelling and its automatics implementation within the modelling scripts. For instance I'm modelling of Rhodopsin-like membrane receptors from GPCR super-family with very slow sequence overlap with the closest templates (up to 20%) so I'm not sure both in automated-generated alignments as well as in the final models. How I could improve quality of both things using iterative concept? Does anybody have experience with the GPCRs modeling ?
Best wishes,
James
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James Starlight