Dear All,
Saira Mian sent this along, does it fit in somehow?
+++++++++++++++++++++++ +++++++++++++++++++++++
http://www.sciencemag.org/cgi/content/full/306/5699/1138 NIH Molecular Libraries Initiative Christopher P. Austin, Linda S. Brady, Thomas R. Insel, and Francis S. Collins austinc@mail.nih.gov
The purpose of the Molecular Libraries Initiative (MLI) component of the NIH Roadmap for Medical Research (1, 2) is to expand the availability, flexibility, and use of small-molecule chemical probes for basic research. ... In exceptional circumstances, the NIH itself might attempt the subsequent steps of drug development, particularly if a small-molecule probe shows special potential for development into a drug for an orphan indication or a disease occurring primarily in the developing world, where there is unlikely to be commercial interest. In this case, NIH Roadmap mechanisms such as the Translational Research Core Services Program and the Regional Translational Research Centers (20) could be used.