Re: [modeller_usage] Model a Tetramer from a Dimer
To:
Subject: Re: [modeller_usage] Model a Tetramer from a Dimer
From: Modeller Caretaker <>
Date: Mon, 22 May 2006 10:31:28 -0700
Cc:
Yun He wrote:
I have read some interesting threads about how to build a multi-chain model,
but these questions are usually focused on building from templates with the
same number of chains. Here is my question, how could I build a tetramer from
a dimer, if any chain of this tetramer is similar to the chain of that dimer.
If you only have a dimer, then Modeller cannot build a tetramer model,
since it doesn't have any information on how the chains interact with
each other. Modeller is not a docking program - you would need to dock
your two dimers together first to make a tetramer. Alternatively, you
could add manual distance restraints to your system to try and pull the
chains together in the right way, but it would be tricky to do correctly.