Hello all,
I am recently became interested in modeling, and I am trying to model a recently discovered protein, that unfortunately appears not to have homologues at all. I tried to run the molecule domain by domain, try to use GenTHREADER, 3DPSSM and several others methods and metaservers to find homologues, but nothing gives an alignment with a reasonable accuracy or p-value. Could somebody recommend me what to do in this case to obtain a reasonable alignment / model?
Any suggestion will be highly appreciated.
Best regards,
Fabian Glaser,
PhD
Bioinformatics Knowledge Unit,
The Lorry I. Lokey
Interdisciplinary
Center for Life Sciences and Engineering
Technion -
Israel Institute of Technology
Haifa 32000, ISRAEL
E-mail: " href="mailto:">" lang="en-us">
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Tel: +972-4-829-3701