[modeller_usage] DOPE score for multi chain protein
To: modeller_usage <>
Subject: [modeller_usage] DOPE score for multi chain protein
From: Omar Piña <>
Date: Tue, 28 Sep 2010 11:39:28 -0500
Hi,
I am modelling a tetrameric protein (ion channel). I want to evaluate the models, but I have read that the DOPE assesment is not good for multi chain proteins (http://www.salilab.org/modeller/9v6/manual/node242.html). Then, how is the best way to evaluate them? Each chain should be evaluated independently? Should I take only the best molpdf score?
In the case of taking only the best molpdf, are there no way for an optimization with DOPE like the Tutorial says?