[Date Prev][Date Next][Thread Prev][Thread Next][Date Index][Thread Index]

Re: [modeller_usage] modelling protein protein interaction

On 07/27/2015 05:45 AM, MARIA VITTORIA CUBELLIS wrote:

I have built a quick model of a mutant.
the protein is a homodimer
mutation in one chain produces a heterodimer

how can I minimize the protein protein interaction site of the heterodimer?

Modeller doesn't model protein-protein interactions. You can certainly 
build a model of your heterodimer though using the homodimer as a 
template (you don't need to do anything special).

	Ben Webb, Modeller Caretaker
--
modeller-care@salilab.org             http://www.salilab.org/modeller/
Modeller mail list: https://salilab.org/mailman/listinfo/modeller_usage