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Re: [modeller_usage] modelling protein protein interaction

On 07/27/2015 05:45 AM, MARIA VITTORIA CUBELLIS wrote:

I have built a quick model of a mutant.
the protein is a homodimer
mutation in one chain produces a heterodimer

how can I minimize the protein protein interaction site of the heterodimer?
Modeller doesn't model protein-protein interactions. You can certainly build a model of your heterodimer though using the homodimer as a template (you don't need to do anything special). 

	Ben Webb, Modeller Caretaker
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