On 6/18/20 9:48 AM, Mariana GONZALEZ MEDINA wrote:
I have a question regarding the zDOPE score. I have read some paper that
state this: "The Z-DOPE scores ranged from −1.63 to −1.85, where a score
of less than −1 indicates a “reliable” model (i.e., 80% of its Cα atoms
are within 3.5 Å of their correct positions)"
I am wondering how is it that a score of less than -1 indicates that 80%
of its Cα atoms are within 3.5 Å of their correct positions?
I would say "implies" rather than "indicates". DOPE is a model
evaluation function. Of course we don't know the true structure so we
can only guess with some degree of confidence (the more negative the
score, the more confident I would be) whether a good DOPE score really
means a correct model. Benchmarking does show that this is typically the
case though; see the DOPE paper.