Re: [modeller_usage] multi-chains: modeled separately or jointly?
To: Amin Zia <>,
Subject: Re: [modeller_usage] multi-chains: modeled separately or jointly?
From: Modeller Caretaker <>
Date: Wed, 25 Nov 2020 14:53:46 -0800
On 11/25/20 10:59 AM, Amin Zia wrote:
In multi-chain modeling, I am wondering if the alignment and modeling
algorithms take into account multiple chains and their spatial locations
concurrently or just simply model each chain separately and then combine
the results.
The entire system is modeled at once.
Related to this, is the dope score assessment a sum of scores for chains
in these cases (in which case, it's assumed the statistics are measuring
two independent models), or the correlation of chains are considered in
the statistical assessment?
The DOPE score is also calculated (by default) for the entire system,
although you could assess each chain separately if you wanted to.