Re: [modeller_usage] Modeling missing residues from a second template file

On 8/15/19 8:25 AM, Danilo Boskovic wrote: > Is it possible? I know that i can model residues according to the > tutorial: select the residues and use as a template to model the full > structure. So i did it and the structure was severely impacted (RMSD > 0.25).

If you really want to do this, note that Modeller by default will try to move all atoms to best satisfy the restraints. If you want the non-missing residues to be exactly the same as the input, make sure you only select the missing residues for refinement in select_atoms(), as per https://salilab.org/modeller/9.22/manual/node23.html

Ben Webb, Modeller Caretaker