Re: [modeller_usage] multi-chains: modeled separately or jointly?

On 11/25/20 10:59 AM, Amin Zia wrote: > In multi-chain modeling, I am wondering if the alignment and modeling > algorithms take into account multiple chains and their spatial locations > concurrently or just simply model each chain separately and then combine > the results.

The entire system is modeled at once.

> Related to this, is the dope score assessment a sum of scores for chains > in these cases (in which case, it's assumed the statistics are measuring > two independent models), or the correlation of chains are considered in > the statistical assessment?

The DOPE score is also calculated (by default) for the entire system, although you could assess each chain separately if you wanted to.

Ben Webb, Modeller Caretaker