Re: [modeller_usage] Fixed amino acids?

On 11/16/15 6:40 AM, Kalantzi Alexandra Styliani wrote: > I would like to build a protein structure based on multiple > homologous proteins. But is it possible to keep few amino acids (main > and side chain) of a homologous structure fixed and build the rest of > the structure around these?

Sure, you can ask Modeller to only refine part of the model; see http://salilab.org/modeller/9.15/manual/node23.html

Ben Webb, Modeller Caretaker