This command will convert the alignment, currently in memory, into the profile format. For more details on the profile format, see Profile.read().
from modeller import * env = Environ() # Read in the alignment file aln = Alignment(env) aln.append(file='toxin.ali', alignment_format='PIR', align_codes='ALL') # Convert the alignment to profile format prf = aln.to_profile() # Write out the profile # in text file prf.write(file='alntoprof.prf', profile_format='TEXT') # in binary format prf.write(file='alntoprof.bin', profile_format='BINARY')