Don't trust modeller ;-)
You could try to impose ideal helix restraints on the helix and see if
that straightens it.
Andrej
--
Andrej Sali, Associate Professor
The Rockefeller University, 1230 York Avenue, New York, NY 10021-6399
tel +1 212 327 7550; lab +1 212 327 7206 ; fax +1 212 327 7540
e-mail ; http://salilab.org
-----Original Message-----
From:
[">mailto:] On Behalf Of Dan
Thomas Major
Sent: Saturday, January 26, 2002 11:40 AM
To:
Subject: Helix kink
Hi,
In my template protein there is a proline in a helix that causes a kink
in the helix. This proline residue does not occur in the target
protein,but modeller predicts a kink in the target protein as well.
Should I "trust" modeller that there is likely to be a kink or is there
a way of dealing with this... Thanks, Dan