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Better Prosa Z-scores for models than template


I have observed an interesting thing with some recently produced models.
When I evaluate them using Prosa, they all have excellent Z-scores (-5.5 to
-6 for 81 residue protein). The strange part is that the template, also 81
residues long and solved to 2 A, has a Z-score of -4.28. When compared
using Procheck, the template and models are just about indistinguishable in
terms of stereochemistry, even though they share only 17% identity (40%
similarity). Is it "normal" that all models have better Prosa Z-scores than
the template, and what could be the reason for this "improvement"?

Thanks for your time,


| Mensur Dlakic, PhD                    | Tel: (734) 764-3554             |
| Department of Biological Chemistry    | Fax: (734) 615-3397             |
| University of Michigan Medical School | http://www.umich.edu/~mensur/   |
| 5416 Medical Science I                | http://myprofile.cos.com/mensur |
| Ann Arbor, MI 48109-0606              | E-mail:         |