Dear Modellers,
I have a monomer sequence A1 that is homologous to the monomer
of a multimer structurer B1....BN. I want to build a model of the multimer
B1....BN with modeller. I can think of two ways ot do this:
1. Divide the pdb files of the multimers B1....BN into single pdb files.
Then I build models on A1...AN matched to them. Then I merge the A1...AN
PDB files to get A1...AN.
2. Model A1 against B1. strcuturally align the structure of A1 against
B1...BN.
My question: is there any way that I can build the multimer A1...AN
in one step against B1...BN?
Thanks and best wishes,
Rich
--------------------------------------------------------------
Richard A. Friedman, PhD
Associate Research Scientist
Herbert Irving Comprehensive Cancer Center
Oncoinformatics Core
Lecturer
Department of Medical Informatics
Box 95, Room 130BB or P&S 1-420C
Columbia University
630 W. 168th St.
New York, NY 10032
(212)305-6901 (5-6901) (voice)
http://cancercenter.columbia.edu/~friedman/
"I wish that all homework was a drawing contest".
-Rose Friedman, age 6