Re: [modeller_usage] The large gap on sequence is a big problem
To:
Subject: Re: [modeller_usage] The large gap on sequence is a big problem
From: Charlotte Habegger-Polomat <>
Date: Wed, 07 Dec 2005 10:12:17 -0500
Cc:
Hello!
I am not sure if you've received any responses to this question yet. I
had a similar problem with the C terminal of my protein that did not
align with any of the templates. The solution I found was to use
secondary structure prediction programs, and since they all pointed
towrds an alpha helix for that region of my protein (based on its
primary sequenmce) I then used restraints on Modeller to "force" that
area into a helix.
I'd be glad to hear how it works out for you!
-Charlotte Habegger-Polomat
Quebec, Canada
นายจิตระยุทธ์ จิตอ่อนน้อม wrote:
Dear Modeller users
I have a big problem in my sequence which has a long gap when i make a
multiple alignment so how modeller solve this problem. Is it built
this model from this gap? or we should cut this gap(but i don't want
to cut this sequence because this sequence is important for looking
the catalytic mechanism. Can any one help me please contact me?.
Thank you
Mr. Jitrayut Jitonnom CSML (Computer Simulation and Modeling Laboratory)
Chiang Mai University
Thailand.