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[modeller_usage] Dope Vs PROSA2003



Hi

If am trying to model loops within my protein model that seem to correspond to regions of high energy in both DOPE and PROSA analysis.
why should it be that aftre modelling the loop with a lower DOPE energy shoud actaully increase in the region of loop modelling with reference to the original model and PROSA analysis?

Any advice much appreciated
Do people generally prefer DOPE or use PROSA and DOPE to complement each other?

Thanks
Jo