[modeller_usage] minimum size of loop for refinement?

[Mike White <>]

Hi

	I have searched the archives for the converse of the "how big is too  
big for loop modeling?"  issue but haven't come across anything. I  
have modeled a protein that has two 1-residue and one 2-residue  
insertions relative to the templates. If the insertions were larger,  
I know that I could use loop modeling to further  refine the model,  
but would much be gained by loop refinement of  such a small region  
(would 1 residue even count as a loop?)? Would extending the "loop"  
by several residues on either side of the insertion be appropriate in  
this case, even if it means allowing residues with corresponding  
positions in the template structure to move?

Thanks!

MIke White