Subject: [modeller_usage] minimize after filling the gaps
From: Mary Varughese <>
Date: Thu, 6 Sep 2012 23:32:55 +0530
Hi, On building the missing residues in a protein(under the option no change to rest of the protein), could i retain the cofactors. Should i minimize the protein as a whole or build region specifically before performing any docking and simulation. I understand the building process itself perform some minimization. Isn't that enough?
Thanking You,
-- Mary Varughese Research Scholar School of Pure and Applied Physics Mahatma Gandhi University India