Hi all,
Last week, based on my Query regarding 'Modelling with Side Chain Restraints', I have prepared my script (see attachment) and built a homology model of a heterotrimer. Eventhough, I restrained the movement of side chains of those copied residues, I failed in keeping my model intact. I mean, my model has got gaps equal to the number of templates. I can say that the templates are not superposed (default by MODELLER) and therefore residues copied from each template have fallen apart with out getting joined to each other. Hope so I have gave a clear idea about the situation. Please let me know if anything more to be provided from my side.
Thanks in Advance
Regards,
Lalith
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Lalith Kumar K
Research Associate,
CADD Division,
Dr. Reddy's Institute of Life Sciences (Formerly known as Institute of Life Sciences)
University of Hyderabad Campus
Gachibowli, Hyderabad 500046, India
Tel: +91 9502074040