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Re: [modeller_usage] Missing Residues Modeling for an Oligomer Inquiry



Hello Ben thank you for your kind update: ). On Tue, Aug 30, 2022 at 5: 45 AM Modeller Caretaker <modeller-care@ salilab. org> wrote: On 8/27/22 12: 03 PM, Joel Subach via modeller_usage wrote: > I am trying to model missing residues for
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Hello Ben thank you for your kind update:).

On Tue, Aug 30, 2022 at 5:45 AM Modeller Caretaker <">> wrote:
On 8/27/22 12:03 PM, Joel Subach via modeller_usage wrote:
> I am trying to model missing residues for a heptamer via the below
> Modeller link, is Modeller able to model these 12-missing residues in
> each of the seven exterior cytoplasmic loop-regions via a properly
> formatted alignment.ali file or would modeling just the missing residues
> for a single monomer work best for Modeller?

Modeller can remodel all chains simultaneously. It may be more efficient
to remodel just the monomer though, particularly if you are working with
a homoheptamer and the missing loops don't interact with each other.

        Ben Webb, Modeller Caretaker
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