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RE: [modeller_usage] modeling a dimer



Yes, you can. The only difference is chain breaks are listed in the
alignment with a "/" (not a "|").

---
Eswar Narayanan, Ph.D
Mission Bay Genentech Hall
600 16th Street, Suite N474Q
University of California, San Francisco
San Francisco, CA 94143-2240 (CA 94158 for courier)
Tel +1 (415) 514-4233; Fax +1 (415) 514-4231
http://www.salilab.org/~eashwar

-----Original Message-----
From: 
[">mailto:] On Behalf Of Rao, Guru
Sent: Thursday, November 13, 2003 6:03 AM
To: 
Subject: [modeller_usage] modeling a dimer

Hi:

I am working with a protein which we have characterized to be a dimer.
Homologous proteins are also dimers and the 3D structures are of the dimeric
forms. In these proteins, the amino acid sequence of the dimer is
represented as A and B chains. Can I model my protein as a dimer by
arranging my sequence as A and B chains with a " | " in between? Would
appreciate some thoughts. Thanks,

Guru Rao


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