Victoria Ann McKenna wrote:
If I was trying to restrain the secondary structure of the target but in some instances this differs from the secondary structure of the template, how would MODELLER restrain, or over ride the restraints of the target (i.e. how does it choose which restraints to use and when?).
Modeller always uses all restraints, so there is no choice to be made here. If you are worried about user-supplied restraints conflicting with the default homology-derived restraints, you can weaken or remove the latter.
Ben Webb, Modeller Caretaker -- http://www.salilab.org/modeller/ Modeller mail list: http://salilab.org/mailman/listinfo/modeller_usage