[Date Prev][Date Next][Thread Prev][Thread Next][Date Index][Thread Index]

Re: [modeller_usage] weight restraints



On 5/27/10 11:28 AM, Roberto Sanchez wrote:
Couldn't one approximate template weighting in a "dirty" way by using
multiple copies of a template in the alignment file? i.e. if template t1
is included in the alignment twice (or maybe even just named twice in
the 'knowns' list in the script, not sure about this) and t2 is used
only once, then effectively the t1 restraint values have twice the
probability of the t2 restraint values (everything else being equal).
Ben, do you think this would work?

Yes, that should work (either way), but like you say, it's dirty. And it still uses the original Modeller weighting scheme - it may be that Armin wants to change that.

	Ben Webb, Modeller Caretaker
--
             http://www.salilab.org/modeller/
Modeller mail list: http://salilab.org/mailman/listinfo/modeller_usage