On 05/02/2011 03:57 AM, Lilit Nersisyan wrote:
The problem is that when I plot the DOPE profiles of the generated models, I see that the template-based segments (especially the 590-781 segment) have the highest energy.
DOPE is an assessment method which aims to tell you how close to native a model structure is. Like any assessment method, it cannot always make this determination with 100% accuracy. Since you know these segments are native-like anyway, I would suggest you trust that information over what DOPE is suggesting.
Ben Webb, Modeller Caretaker -- http://www.salilab.org/modeller/ Modeller mail list: http://salilab.org/mailman/listinfo/modeller_usage