photo: © majedphoto.com

Andrej Sali

Professor

Steve Ha

Ignacia Echeverria

Assistant Adjunct Professor

• Integrative structure determination of the Nuclear Pore Complex.
• Characterizing host-pathogen interactions using data from different sources.
• Leveraging large-scale genetic interaction mapping to model the structures of protein assemblies.

Kenneth Huang

Postdoctoral Scholar

• Modeling multi state ensemble of the Nsp2 protein
• Integrative meta-modeling of the nuclear pore complex

Atreya Dey

Postdoctoral Scholar

• Method development for IMP
• Analysis of deep mutational scanning data

Arthur Zalevsky

Postdoctoral Scholar

• Development of the PDB-Dev repository of integrative structures
• Integrative modeling of biomolecular assemblies guided by chemical crosslinking and electron microscopy data

Vipul Kumar

Postdoctoral Scholar

• Development and Application of IMP for Integrative Modeling of Prion-Associated Macromolecular Assemblies
• Development and Application of Integrative Modeling to Integrate Cryo-ET and Footprinting Data
• Modeling and High-Throughput Virtual Screening of Molecules Against Transport Proteins

Sree Ganesh Balasubramani

Postdoctoral Scholar

• Bayesian hierarchical modeling of protein structures using data from in vivo experiments

Neelesh Soni

Postdoctoral Scholar

• Development and application of IMP for integrative modeling of macromolecular assemblies
• Integrative modeling of NPC and its sub-complexes
• Development of tools for microenvironment mapping

Andrew Latham

Postdoctoral Scholar

• Spatiotemporal integrative modeling of macromolecular assemblies.
• Characterizing the nuclear pore complex assembly pathway

Abantika Pal

Postdoctoral Scholar

• Modeling the structures of protein assemblies utilizing hierarchical mapping of cell architecture.
• Application of IMP for integrative modeling of biomolecular assemblies associated with cancer.

Eli Draizen

Postdoctoral Scholar

• Bayesian Meta-modeling with deep generative models.
• Protein-protein interactions and whole cell modeling.
• Explainable AI for protein evolution.

Surabhi Rathore

Postdoctoral Scholar

• Method development to utilize CRISPR-a, CRISPR-n, and SEC-MS data as network and spatial restraints for integrative modeling of HIV-host protein interaction networks and structures.
• Integrative modeling of human TRIM5a-HIV1 capsid using DMS data.

Jared Sagendorf

Postdoctoral Scholar

Eliot Jefferys

Postdoctoral Scholar

Vikas Tiwari

Postdoctoral Scholar

Aji Palar

Graduate Student

Graduate Program in Biophysics

• Integrative structural biology of host-pathogen complexes
• Integrative network modeling

Matthew Hancock

Graduate Student

Graduate Program in Biophysics

• Integrative modeling of macromolecular ensembles
• Thermodynamic approximations from structural ensembles

Mark Ware

Graduate Student

Ben Webb

Academic Coordinator

• Development of the Modeller package for comparative modeling.
• Development of the IMP platform for assemblies and modeling.
• Refinement of protein structure models.
• Systems administration.