Karin Asensio |
Analyst |
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David Barkan |
Graduate Student |
Graduate Program in Biological and Medical Informatics |
- I am interested in improving and applying bioinformatics methods to predict protein-protein interaction specificity. I am currently predicting novel protein interaction partners in two biological systems. The first is the type three secretion system that pathogenic bacteria employ to translocate virulence proteins into host cells, and the other is with proteins involved in lymphocyte-mediated apoptotic pathways, searching for unidentified substrates of the serine protease Granzyme B.
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Hao Fan |
Postdoctoral Scholar |
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- Structure prediction on protein-ligand complex
- Small compound virtual screening using comparative models of proteins
- Structure and function prediction of amidohydrolase
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Seung-Joong Kim |
Postdoctoral Scholar |
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- Development of the TNT module
- Ab initio protein folding prediction
- Integration of SAXS (Small Angle X-ray Scattering) data into structural modelling of proteins and their assemblies
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Keren Lasker |
Junior Specialist |
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- Modeling structures of large assemblies by integrating cryo-electron microscopy data with other sources of information.
- Developing a coarse-grained optimization protocol for characterizing structures of assemblies at different levels of resolution.
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Adam C. Marko |
Graduate Student |
Graduate Program in Biological and Medical Informatics |
- Protein structure prediction as part of the TNT module
- Modeling of G Protein-Coupled Receptors (GPCRs)
- Development of statistical potentials for GPCR evaluation
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Mark Peterson |
Graduate Student |
Graduate Program in Biological and Medical Informatics |
- comparing sequence-structure relationships in orthologs vs. paralogs
- developing new methods for improving weighting of multiple templates for comparative modeling
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Jeremy Phillips |
Graduate Student |
Graduate Program in Biological and Medical Informatics |
- Restrained protein-protein docking in the context of large macromolecular assemblies
- Work toward a higher resolution of the structure of the Nuclear Pore Complex (NPC) by integration of diverse experimental data and computational modeling.
- Docking applications of the integrated modeling platform (IMP)
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Associate Researcher |
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- ModBase: A database of comparative protein structure models
- Target Selection and Annotation for Structural Genomics
- Comparative models for Molecular Replacement
- Systems Administration
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Postdoctoral Scholar |
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- integrative modeling of the dynamics of transport through the NPC
- optimizing the representational level of detail when modeling assemblies
- kinetic data structures and other means of maintaining geometric data structures on moving primitives
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Lab Head |
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Avner Schlessinger |
Postdoctoral Scholar |
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- Determine substrate specificity within and across SLC families using
sequence- and structure-based approaches.
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Dina Schneidman |
Postdoctoral Scholar |
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- structural characterization of protein assemblies
- dynamics of protein folding
- antibody-antigen interactions
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Javier Velazquez-Muriel |
Postdoctoral Scholar |
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- Ab-initio predicition of proteins with additional experimental data. Example, EM-maps.
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Research Associate |
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- Development of the Modeller package for comparative modeling.
- Development of the IMP platform for assemblies and modeling.
- Refinement of protein structure models.
- Systems administration.
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