modeller_usage

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September 2019

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Homology modeling with low sequence identity and missing loops in template
by Ahmad Khalifa 05 Sep '19

05 Sep '19

Hello, I have two sequences with low sequence identity and I get an alignment in modeller different than clustalW, which also differs from when I use emboss matcher. I also have a missing segment in my template, I want the final model to have the corresponding segments and the gaps unmodeled, same as the template. I tried to modify the alignment manually, however I ran into the "SequenceMismatchError: read_te_291E> Sequence difference between alignment and pdb :" error, which I think has … [View More]

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