Dear Modeller users,

I was wondering if others would share how many structures you usually generate for a family of models.

I am currently working on modelling my protein of interest with 3 known template structures (>30% sequence similarity). When using Modeller, I generate a family of 20 models and then evaluate the variability and quality of models within the family.

How many do other Modeller users generate?

How do you decide on this number?

I've read articles where 3 models, others where 30 models were generated with Modeller...

Thanks!

-Charlotte Habegger-Polomat