hello, can anybody suggest me anything about my problem? i am trying to model the structure of an oxidoreductase enzyme, for which thetemplate is of lenth shorter than the query sequence. last 47 amino acid residues at c-terminus of the protein didnot match wiht any template structure, and there are chances of these residues to be involved in formation of active site. so is there any method by which i can model this lenght of residues without alignment with any 3d structure?
Archana Chavan wrote: > can anybody suggest me anything about my problem? > i am trying to model the structure of an oxidoreductase enzyme, for > which thetemplate is of lenth shorter than the query sequence. > last 47 amino acid residues at c-terminus of the protein didnot match > wiht any template structure, and there are chances of these residues to > be involved in formation of active site. so is there any method by which > i can model this lenght of residues without alignment with any 3d > structure?
If you don't have a template, then you are unlikely to be able to get a high quality model, since you essentially have to solve the protein folding problem.
Ben Webb, Modeller Caretaker
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Archana Chavan -
Modeller Caretaker