Hi Modellers,
I have a question regarding the objective function in the output file(.B99....) of MODELLER.
I've been evaluating the models that run by MODELLER. I selected three best models from my running results based on their objective function( the lower the better). Each objective function of them is like following: A: 6103.3325, B: 6090.5195, C: 6077.6436.
Then I used ProsaII to calulate the z- scores after I did CHARRM energy minimization. The zp-comb of them are A: -5.69, B: -3.82, C: -5.87.
>From Modeller I can see B and C might have better models than A does. But from ProsaII, I can exclude B. Does this kind of thing happen before? I'd like to know if I should include as many as models I have to run Prosa, in case the models with higher objective functions have lower z-scores. Thank you very much.
Sincerely, Violet