Dear modellers, I modelled protein using modeller to get initial models,after evaluating, I made correction in models using the SPDBV Software,since it gives visulization option for interactive adjustment of the model. Now my question is # Is it theoreticaly correct to adopt differnet force feild for Energy minimization at various stage of the model building methadology ?(As I produced my initial model in modeller where the optimization used the CHARMM force field,but in SPDBV implements GROMOS96 as force filed. So I did energy minimization of the model in SPDBV for some sterochemical adustment made in the modeled structure.) Yours truly, B.Nataraj
B.Nataraj, Final year M.Tech.(Bioinformatics), SASTRA Deemed University, (www.sastra.edu) Thanjavur, Tamil Nadu, India. Email:nataraj@biotech2.sastra.edu Email:natarajmtech@yahoo.co.uk --------------------------------- Yahoo! Messenger - Communicate instantly..."Ping" your friends today! Download Messenger Now