13 Oct
2002
13 Oct
'02
11:58 p.m.
Dear modellers:
I have modelled a molecule successfully using modeller. This molecule forms dimers, probably very similar as it occurs with the template molecule, and I would like to optimize my model to improve the dimerization surface and intersubunit contacts. Which would be the best strategy to do it so?. How can I restrain changes in one subunit to be exactly modelled in the other subunit?.
Many thanks in advance for your suggestions,
Santiago
*********************************************** Santiago Ramón-Maiques Instituto de Biomedicina de Valencia Consejo Superior de Investigaciones CientÃficas C/ Jaime Roig, 11 46010 Valencia, Spain ***********************************************