Hello,
I have a crosslinking MS dataset beteween 3 proteins, A, B and C. B
and C are different proteins that share 30% identical sequence in
chunks. Thus, I have crosslinks from A to B that are unambiguous, and
others that may be from A to B or from A to C, as they go to a shared
sequence. For homodimers, IMP handles this automatically.
How do I construct the crosslink database to specify ambiguity at the
restraint level? is there a column I can add to the crosslink csv that
has a a selection e.g. residue 5 of protein A is crosslinked to
residue 17 of protein B or residue 29 of protein C?
Many thanks,
Andrea
